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首页-抗体和重组蛋白-Biosimilar Antibody-Sintilimab
Sintilimab

Chemical Structure : Sintilimab

CAS No.: 2072873-06-2

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Sintilimab (Anti-human PD-1 mAb, human IgG4P-Kappa; IBI-308)

货号: PC-Ab1104Not For Human Use, Lab Use Only.

Sintilimab (IBI 308) is a type of immunoglobulin G4 monoclonal antibody, which binds to PD-1 molecules on the surface of T-cells, blocks the PD-1 / PD-Ligand 1 (PD-L1) pathway, and reactivates T-cells to kill cancer cells. .

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1 mg ￥3580 In stock
5 mg ￥7580 In stock
10 mg ￥12800 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Sintilimab (IBI 308) is a type of immunoglobulin G4 monoclonal antibody, which binds to PD-1 molecules on the surface of T-cells, blocks the PD-1 / PD-Ligand 1 (PD-L1) pathway, and reactivates T-cells to kill cancer cells.

物理化学性质&存储条件

分子量
分子式 Human IgG4P-Kappa
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives
Chemical Name/SMILES

Sintilimab; Tyvyt; IBI 308; IBI-308; 2072873-06-2; Anti-human programmed death receptor-1; Anti-human PD1

参考文献

1. 1, Wang J, et al. MAbs. 2019 Nov-Dec;11(8):1443-1451.  2, Shi Y, et al. Lancet Haematol. 2019 Jan;6(1):e12-e19. 3, Zhang L, et al. Front Oncol. 2020 Nov 26;10:594558.  4, Jiang H, et al. BMC Cancer. 2020 Aug 14;20(1):760.

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