Simpinicline (OC-02)

Chemical Structure : Simpinicline

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货号: PC-38681Not For Human Use, Lab Use Only.

Simpinicline (OC-02) is a highly selective nicotinic acetylcholine receptor (nAChR) agonist, exhibits potent antiviral activity against the SARS-CoV-2 variants in cell culture with IC50 of 40 nM.

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100 mg		Get quote

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生物&药学活性

Simpinicline (OC-02) is a highly selective nicotinic acetylcholine receptor (nAChR) agonist, exhibits potent antiviral activity against the SARS-CoV-2 variants in cell culture with IC50 of 40 nM.

物理化学性质&存储条件

分子量	175.235
分子式	C10H13N3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-{(1E)-2-[(3R)-pyrrolidin-3-yl]ethen-1-yl}pyrimidine

参考文献

1. Alexandris, N. et al. Toxicology reports, 8, 73-83.

2. Sungnak, W.,et al. Nature medicine, 26(5), 681-687.