Shield-1 |CAS:914805-33-7 Probechem Biochemicals

Chemical Structure : Shield-1

CAS No.: 914805-33-7

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Shield-1 (Shld-1;Shield 1;Shield 1)

货号: PC-60184Not For Human Use, Lab Use Only.

Shield-1 is a cell-permeable FKBP ligand that is designed to protect an otherwise unstable protein domain from degradation.

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2 mg	￥1780	In stock
5 mg	￥2880	In stock
10 mg	￥4580	In stock
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100 mg		Get quote

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生物&药学活性

Shield-1 is a cell-permeable FKBP ligand that is designed to protect an otherwise unstable protein domain from degradation.
Shield-1 binds tightly to FKBP, induces rapid and processive degradation of the LID domain and any fused partner protein.

物理化学性质&存储条件

分子量	748.9
分子式	C42H56N2O10
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-(R)-3-(3,4-Dimethoxyphenyl)-1-(3-(2-morpholinoethoxy)phenyl) propyl 1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carboxylate

参考文献

1. Banaszynski, et al. Cell. 2006 Sep 8; 126(5):995-1004.

2. Rodriguez S, et al. Chem Biol. 2012 Mar 23;19(3):391-8.

3. Bonger KM, et al. Nat Chem Biol. 2011 Jul 3;7(8):531-7.

Shield-1 (Shld-1;Shield 1;Shield 1)

生物&药学活性

物理化学性质&存储条件

参考文献

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Shield-1 (Shld-1;Shield 1;Shield 1)

生物&药学活性

物理化学性质&存储条件

参考文献

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