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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-SGLT-Sergliflozin etabonate
Sergliflozin etabonate

Chemical Structure : Sergliflozin etabonate

CAS No.: 408504-26-7

Sergliflozin etabonate (GW869682X)

货号: PC-20194Not For Human Use, Lab Use Only.

Sergliflozin etabonate (GW869682X) is a potent, selective SGLT2 inhibitor with IC50 of 7.5 nM (hSGLT2), >200-fold selectivity over hSGLT1.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Sergliflozin etabonate (GW869682X) is a potent, selective SGLT2 inhibitor with IC50 of 7.5 nM (hSGLT2), >200-fold selectivity over hSGLT1.

物理化学性质&存储条件

分子量 448.46
分子式 C23H28O9
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

ethyl (((2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(2-(4-methoxybenzyl)phenoxy)tetrahydro-2H-pyran-2-yl)methyl) carbonate

参考文献

1. Katsuno K, et al. J Pharmacol Exp Ther. 2007 Jan;320(1):323-30.

2. Pajor AM, et al. J Pharmacol Exp Ther. 2008 Mar;324(3):985-91.

3. Fujimori Y, et al. Eur J Pharmacol. 2009 May 1;609(1-3):148-54.

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