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首页-小分子抑制剂&激动剂-Others-Other Targets-Sepin-1
Sepin-1

Chemical Structure : Sepin-1

CAS No.: 163126-81-6

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Sepin-1 (Sepin1)

货号: PC-62753Not For Human Use, Lab Use Only.

Sepin-1 is a small molecule, noncompetitive separase inhibitor with IC50 of 14.8 uM.

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5 mg ￥880 In stock
10 mg ￥1280 In stock
25 mg ￥2180 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Sepin-1 is a small molecule, noncompetitive separase inhibitor with IC50 of 14.8 uM.
Sepin-1 inhibits the growth of human cancer cell lines and breast cancer xenograft tumors in mice by inhibiting cell proliferation and inducing apoptosis.

物理化学性质&存储条件

分子量 223.188
分子式 C9H9N3O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2,2-dimethyl-5-nitro-2H-benzo[d]imidazole 1,3-dioxide

参考文献

1. Do HT, et al. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4446-50.

2. Zhang N, et al. J Biomol Screen. 2014 Jul;19(6):878-89.

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