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Senktide

Chemical Structure : Senktide

CAS No.: 106128-89-6

Senktide (NK3R antagonist)

货号: PC-63134Not For Human Use, Lab Use Only.

Senktide is a potent, selective agonist of neuromedin K3 (NK3) receptor (EC50 =0.5-3 nM), less potently agonizes the NK1 receptor (EC50=35 µM) and is without effect on the NK2 receptor.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Senktide is a potent, selective agonist of neuromedin K3 (NK3) receptor (EC50 =0.5-3 nM), less potently agonizes the NK1 receptor (EC50=35 µM) and is without effect on the NK2 receptor.

物理化学性质&存储条件

分子量 841.978
分子式 C40H55N7O11S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

DFFGLM (Modifications: Asp-1 = Succinyl-Asp, Phe-3 = Me-Phe, Met-6 = C-terminal amide)

参考文献

1. Byk G, et al. J Med Chem. 1996 Aug 2;39(16):3174-8.

2. Sarau HM, et al. J Pharmacol Exp Ther. 1997 Jun;281(3):1303-11.

3. Harrison T, et al. Bioorg Med Chem Lett. 1998 Jun 2;8(11):1343-8.

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