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首页-小分子抑制剂&激动剂-JAK/STAT Signaling-STAT-Scutellarin
Scutellarin

Chemical Structure : Scutellarin

CAS No.: 27740-01-8

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Scutellarin

货号: PC-23197Not For Human Use, Lab Use Only.

Scutellarin is an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts, also shows anti-HIV-1 activity.

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25 mg ￥780 In stock
50 mg ￥1280 In stock
100 mg ￥1980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Scutellarin is an active flavone isolated from Scutellaria baicalensis, can down-regulates the STAT3/Girdin/Akt signaling in HCC cells, and inhibits RANKL-mediated MAPK and NF-κB signaling pathway in osteoclasts, also shows anti-HIV-1 activity.

物理化学性质&存储条件

分子量 462.36
分子式 C21H18O12
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(2S,3S,4S,5R,6S)-6-((5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid

参考文献

1. Ke Y, et al. Biochem Biophys Res Commun. 2016 Dec 18.

2. Zhao S, et al. Int Immunopharmacol. 2016 Nov;40:458-465

3. Zhang GH, et al. Biochem Biophys Res Commun. 2005 Sep 2;334(3):812-6.

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