Saroglitazar magnesium salt

Chemical Structure : Saroglitazar magnesium salt

CAS No.: 1639792-20-3

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货号: PC-45753Not For Human Use, Lab Use Only.

Saroglitazar magnesium salt is a small molecule PPAR agonist with predominant PPARα and moderate PPARγ activity with EC50 of 0.65 pM and 3 nM respectively.

规格	价格	库存
5 mg	￥1380	In stock
10 mg	￥2180	In stock
25 mg	￥3880	In stock
50 mg	￥5880	In stock
100 mg		Get quote

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生物&药学活性

Saroglitazar magnesium salt is a small molecule PPAR agonist with predominant PPARα and moderate PPARγ activity with EC50 of 0.65 pM and 3 nM respectively.
Saroglitazar has been developed for the treatment of dyslipidaemia and has favourable effects on glycaemic parameters in type 2 diabetes mellitus.

物理化学性质&存储条件

分子量	450.71
分子式	C25H28NO4S.1/2Mg
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzenepropanoic acid, α-ethoxy-4-[2-[2-methyl-5-[4-(methylthio)phenyl]-1H-pyrrol-1-yl]ethoxy]-,magnesium salt (2:1),(αS)-,

参考文献

1. Agrawal R. Curr Drug Targets. 2014 Feb;15(2):151-5.

2. Jani RH, et al. Clin Drug Investig. 2013 Nov;33(11):809-16.

3. Jain MR, et al. Pharmacol Res Perspect. 2015 Jun;3(3):e00136.