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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-PPAR-Saroglitazar
Saroglitazar

Chemical Structure : Saroglitazar

CAS No.: 495399-09-2

Saroglitazar (PPARα agonist)

货号: PC-45752Not For Human Use, Lab Use Only.

Saroglitazar is a PPAR agonist with predominant PPARα and moderate PPARγ activity with EC50 of 0.65 pM and 3 nM respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Saroglitazar is a PPAR agonist with predominant PPARα and moderate PPARγ activity with EC50 of 0.65 pM and 3 nM respectively.
Saroglitazar has been developed for the treatment of dyslipidaemia and has favourable effects on glycaemic parameters in type 2 diabetes mellitus.

物理化学性质&存储条件

分子量 439.567
分子式 C25H29NO4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: 10 mM

Chemical Name/SMILES

Benzenepropanoic acid, α-ethoxy-4-[2-[2-methyl-5-[4-(methylthio)phenyl]-1H-pyrrol-1-yl]ethoxy]-, (αS)-

参考文献

1. Agrawal R. Curr Drug Targets. 2014 Feb;15(2):151-5.

2. Jani RH, et al. Clin Drug Investig. 2013 Nov;33(11):809-16.

3. Jain MR, et al. Pharmacol Res Perspect. 2015 Jun;3(3):e00136.

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