Sardomozide dihydrochloride | SAMDC inhibitor | Probechem Biochemicals

Chemical Structure : Sardomozide dihydrochloride

CAS No.: 138794-73-7

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Sardomozide dihydrochloride (SAM486A)

货号: PC-24845Not For Human Use, Lab Use Only.

SAM486A dihydrochloride (Sardomozide) is a highly potent, selective S-adenosylmethionine decarboxylase (SAMDC) inhibitor with IC50 of 5 nM, inhibits intracellular spermidine and spermine pools.

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5 mg	￥980	In stock
10 mg	￥1480	In stock
25 mg	￥2580	In stock
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100 mg		Get quote

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生物&药学活性

SAM486A dihydrochloride (Sardomozide) is a highly potent, selective S-adenosylmethionine decarboxylase (SAMDC) inhibitor with IC50 of 5 nM, inhibits intracellular spermidine and spermine pools.
SAM486A (Sardomozide) shows a pronounced antiproliferative activity (IC50 of 0.71 uM, human T24 bladder carcinoma cells).
SAM486A (Sardomozide) displays >2500-fold selective over diamine oxidase (DAO).

物理化学性质&存储条件

分子量	303.19
分子式	C11H16Cl2N6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(4-Carbamimidoyl-2,3-dihydro-1H-inden-1-ylidene)hydrazine-1-carboximidamide dihydrochloride

参考文献

1. Stanek J, et al. J Med Chem. 1993 Jul 23;36(15):2168-71.

2. Regenass U, et al. Cancer Res. 1994 Jun 15;54(12):3210-7.

Sardomozide dihydrochloride (SAM486A)

生物&药学活性

物理化学性质&存储条件

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Sardomozide dihydrochloride (SAM486A)

生物&药学活性

物理化学性质&存储条件

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