Saquinavir mesylate |CAS:149845-06-7 Probechem Biochemicals

Chemical Structure : Saquinavir mesylate

CAS No.: 149845-06-7

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Saquinavir mesylate (Ro 31-8959/003)

货号: PC-45129Not For Human Use, Lab Use Only.

Apotent and selective inhibitor of HIV-1 protease with IC50 of 0.5-6 nM in cell assays.

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50 mg	￥1960	In stock
250 mg		Get quote

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生物&药学活性

Apotent and selective inhibitor of HIV-1 protease with IC50 of 0.5-6 nM in cell assays; binds to the active site of the viral protease and prevents cleavage of viral polyproteins, preventing maturation of the virus; inhibits both HIV-1 and HIV-2 proteases; used to treat or prevent HIV/AIDS.

HIV Infection

Approved

物理化学性质&存储条件

分子量	766.9465
分子式	C39H54N6O8S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Butanediamide, N1-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]-, (2S)-, methanesulfonate (1:1)

参考文献

1. Martin JA, et al. Biochem Biophys Res Commun. 1991 Apr 15;176(1):180-8.

2. Craig JC, et al. Antiviral Res. 1991 Dec;16(4):295-305.

3. Kräusslich HG. J Virol. 1992 Jan;66(1):567-72.

Saquinavir mesylate (Ro 31-8959/003)

生物&药学活性

物理化学性质&存储条件

参考文献

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Saquinavir mesylate (Ro 31-8959/003)

生物&药学活性

物理化学性质&存储条件

参考文献

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