Sapacitabine |CAS:151823-14-2 Probechem Biochemicals

Chemical Structure : Sapacitabine

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Sapacitabine (CYC-682;CYC682)

货号: PC-61331Not For Human Use, Lab Use Only.

An orally available, nucleoside analog prodrug of CNDAC that interferes with DNA synthesis by causing single-strand DNA breaks.

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生物&药学活性

An orally available, nucleoside analog prodrug of CNDAC that interferes with DNA synthesis by causing single-strand DNA breaks; induces arrest of the cell division cycle at G2 phase, demonstrates potent anti-tumor activity in both blood and solid tumors.

Chemotherapeutic Agents

Phase 3 Clinical

物理化学性质&存储条件

分子量	490.64
分子式	C26H42N4O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[1-(2-Cyano-2-deoxy-β-D-arabinofuranosyl)-1,2-dihydro-2-oxo-4-pyrimidinyl]hexadecanamide

参考文献

1. Hanaoka K, et al. Int J Cancer. 1999 Jul 19;82(2):226-36.

2. Wu M, et al. Cancer Res. 2003 May 15;63(10):2477-82.

3. Katz MH, et al. Cancer Res. 2003 Sep 1;63(17):5521-5.

Sapacitabine (CYC-682;CYC682)

生物&药学活性

物理化学性质&存储条件

参考文献

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Sapacitabine (CYC-682;CYC682)

生物&药学活性

物理化学性质&存储条件

参考文献

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