Salinomycin sodium |CAS:55721-31-8 Probechem Biochemicals

Chemical Structure : Salinomycin sodium

CAS No.: 55721-31-8

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Salinomycin sodium (Sodium salinomycin)

货号: PC-45261Not For Human Use, Lab Use Only.

规格	价格	库存
25 mg	￥580	In stock
100 mg	￥980	In stock
250 mg		Get quote
1 g		Get quote

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生物&药学活性

Salinomycin sodium is a polyether ionophore antibacterial agent that shows effects on mitochondrial ion translocation and respiration, inhibits Wnt/β-catenin signaling, blocks Wnt-induced LRP6 phosphorylation and induces ferroptosis in cancer cells.
Salinomycin sodium inhibits Wnt signaling and selectively induces apoptosis in chronic lymphocytic leukemia cells.
Salinomycin sodium induces ER stress‑mediated autophagy and apoptosis through generation of ROS in human glioma U87MG cells.

物理化学性质&存储条件

分子量	772.9804
分子式	C42H69NaO11
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	DMSO: ≥ 15 mg/mL
Chemical Name/SMILES	Salinomycin, sodium salt (1:1)

参考文献

1. Mitani M, et al. Antimicrob Agents Chemother. 1976 Apr;9(4):655-60.

2. Lu D, et al. Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13253-7.

3. Yu SN, et al. Oncol Rep. 2017 Jun;37(6):3321-3328.

Salinomycin sodium (Sodium salinomycin)

生物&药学活性

物理化学性质&存储条件

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Salinomycin sodium (Sodium salinomycin)

生物&药学活性

物理化学性质&存储条件

参考文献

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