Sacubitril | Neprilysin inhibitor | Probechem Biochemicals

Chemical Structure : Sacubitril

CAS No.: 149709-62-6

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货号: PC-28475Not For Human Use, Lab Use Only.

Sacubitril (AHU-377) is a potent and orally active neprilysin (NEP) inhibitor with IC50 of 5 nM, a component of the Sacubitril/Valsartan (LCZ696).

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Sacubitril (AHU-377) is a potent and orally active neprilysin (NEP) inhibitor with IC50 of 5 nM, a component of the Sacubitril/Valsartan (LCZ696).

分子量	411.50
分子式	C24H29NO5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(((2S,4R)-1-([1,1'-Biphenyl]-4-yl)-5-ethoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid

1. Gu J, et al. J Clin Pharmacol. 2010 Apr;50(4):401-14.