Chemical Structure : Sacituzumab
CAS No.: 1796566-95-4
货号: PC-Ab1045Not For Human Use, Lab Use Only.
Sacituzumab is a human Trop-2 mAB that targets the Trop-2 protein and attaches to it. Sacituzumab govitecan is an antibody–drug conjugate composed of an antibody targeting the human trophoblast cell-surface antigen 2 (Trop-2), which is expressed in the majority of breast cancers, coupled to SN-38 (topoisomerase I inhibitor) through a proprietary hydrolyzable linker..
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
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Sacituzumab is a human Trop-2 mAB that targets the Trop-2 protein and attaches to it. Sacituzumab govitecan is an antibody–drug conjugate composed of an antibody targeting the human trophoblast cell-surface antigen 2 (Trop-2), which is expressed in the majority of breast cancers, coupled to SN-38 (topoisomerase I inhibitor) through a proprietary hydrolyzable linker.
分子量 | ||
分子式 | Human IgG1-Kappa | |
外观性状 | Solid | |
储存条件 |
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Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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Chemical Name/SMILES |
Sacituzumab; Sacituzumab Govitecan; TACSTD2; Trop-2; trophoblast cell-surface antigen 2; Tumor Associated Calcium Signal Transducer 2 |
1. 1, Bardia A, et al. N Engl J Med. 2019 Feb 21;380(8):741-751. 2, Fenn KM, et al. Drugs Today (Barc). 2019 Sep;55(9):575-585. 3, Goldenberg DM, et al. MAbs. 2019 Aug/Sep;11(6):987-995. 4, Kalinsky K, et al. Ann Oncol. 2020 Dec;31(12):1709-1718.
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