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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-SYM2081
SYM2081

Chemical Structure : SYM2081

CAS No.: 31137-74-3

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SYM2081 (SYM-2081)

货号: PC-23690Not For Human Use, Lab Use Only.

SYM2081 is a potent, specific agonist of glutamate receptor ionotropic kainate 2 (GluK2) with EC50 of 0.2 uM, inhibits inhibits [3H]-kainate binding with IC50 of 35 nM.

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10 mg ￥2180 In stock
25 mg ￥3880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SYM2081 is a potent, specific agonist of glutamate receptor ionotropic kainate 2 (GluK2) with EC50 of 0.2 uM, inhibits inhibits [3H]-kainate binding with IC50 of 35 nM.

物理化学性质&存储条件

分子量 161.16
分子式 C6H11NO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(2S,4R)-2-Amino-4-methylpentanedioic acid

参考文献

1. Carver JM, et al. Brain Res. 1996 May 13;720(1-2):69-74.

2. Zhang YR, et al. Sci Transl Med. 2024 Dec 11;16(777):eadq9133.

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