SX-576 |CAS:1240494-14-7 Probechem Biochemicals

首页-小分子抑制剂&激动剂-GPCR-Chemokine Receptor (CCR and CXCR)-SX-576

Chemical Structure : SX-576

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SX-576 (SX 576;SX576)

货号: PC-60619Not For Human Use, Lab Use Only.

SX-576 is a potent, equipotent CXCR1 and CXCR2 antagonist with IC50 of 31 nM and 21 nM, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SX-576 is a potent, equipotent CXCR1 and CXCR2 antagonist with IC50 of 31 nM and 21 nM, respectively.
SX-576 exhibits potent inhibition of neutrophil influx in rat model of pulmonary inflammation.

物理化学性质&存储条件

分子量	466.214
分子式	C20H15BF4N2O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2-(((5-((4-fluorophenyl)carbamoyl)pyridin-2-yl)thio)methyl)-4-(trifluoromethoxy)phenyl)boronic acid

参考文献

1. Maeda DY, et al. Bioorg Med Chem Lett. 2015 Jun 1;25(11):2280-4.

2. Schuler AD, et al. Bioorg Med Chem Lett. 2015 Sep 15;25(18):3793-7.

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SX-576 (SX 576;SX576)

生物&药学活性

物理化学性质&存储条件

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SX-576 (SX 576;SX576)

生物&药学活性

物理化学性质&存储条件

参考文献

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