SW222746 | 15-PGDH inhibitor | Probechem Biochemicals

Chemical Structure : SW222746

加入收藏

SW222746 (SW 222746, 15-PGDH inhibitor 49)

货号: PC-49523Not For Human Use, Lab Use Only.

SW222746 (SW 222746) is a potent selective, orally active inhibitor of 15-Prostaglandin dehydrogenase (15-PGDH) with IC50 of 3 nM.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

SW222746 (SW 222746) is a potent selective, orally active inhibitor of 15-Prostaglandin dehydrogenase (15-PGDH) with IC50 of 3 nM.
15-PGDH inhibitor 49 shows potent inhibition of 15-PGDH, good oral bioavailability, and protective activity in mouse models of ulcerative colitis and recovery from bone marrow transplantation.

物理化学性质&存储条件

分子量	398.47
分子式	C24H22N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-methyl-6-(7-(piperidine-1-carbonyl)quinoxalin-2-yl)isoquinolin-1(2H)-one

参考文献

1. Bin Hu, et al. J Med Chem. 2022 Nov 24;65(22):15327-15343.
2. Wei Huang, et al. Nat Commun. 2023 Feb 11;14(1):784.

SW222746 (SW 222746, 15-PGDH inhibitor 49)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

SW222746 (SW 222746, 15-PGDH inhibitor 49)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.