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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Stearoyl-CoA Desaturase (SCD)-SW203668
SW203668

Chemical Structure : SW203668

CAS No.: 1673556-40-5

SW203668 (SW 203668)

货号: PC-20380Not For Human Use, Lab Use Only.

SW203668 (SW 203668) is a potent, tumor-specific, irreversible stearoyl CoA desaturase (SCD) inhibitor with high sensitity to H2122 cell (IC50=22 nM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    SW203668 (SW 203668) is a potent, tumor-specific, irreversible stearoyl CoA desaturase (SCD) inhibitor with high sensitity to H2122 cell (IC50=58 nM).
    SW203668 shows selective and potent cytotoxicity against cancer cell lines expressing cytochrome P450 4F11.

    物理化学性质&存储条件

    分子量 389.47
    分子式 C22H19N3O2S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-(amino(phenyl)methyl)-N-(6-methoxybenzo[d]thiazol-2-yl)benzamide

    参考文献

    1. JM, et al. Nat Chem Biol. 2016 Apr;12(4):218-25.

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