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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Topoisomerase-SW-044248
SW-044248

Chemical Structure : SW-044248

CAS No.: 522650-83-5

SW-044248 (SW 044248;SW044248)

货号: PC-45667Not For Human Use, Lab Use Only.

SW-044248 is a potent, selective inhibitor of Topoisomerase I (Topo I), inhibits Top I differently from camptothecin, shows selective toxicity for some NSCLC cell lines.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SW-044248 is a potent, selective inhibitor of Topoisomerase I (Topo I), inhibits Top I differently from camptothecin, shows selective toxicity for some NSCLC cell lines.

物理化学性质&存储条件

分子量 421.5153
分子式 C22H23N5O2S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 30 mg/mL

Chemical Name/SMILES

Butanamide, 2-[(5-ethyl-5H-1,2,4-triazino[5,6-b]indol-3-yl)thio]-N-(2-methoxyphenyl)-

参考文献

1. Zubovych IO, et al. Mol Cancer Ther. 2016 Jan;15(1):23-36.

2. Kim HS, et al. Cell. 2013 Oct 24;155(3):552-66.

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