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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-DNA Repair Protein -SU0617
SU0617

Chemical Structure : SU0617

CAS No.:

SU0617 (SU-0617)

货号: PC-27097Not For Human Use, Lab Use Only.

SU0617 is a specific small molecule inhibitor of DNA repair enzyme SMUG1 with IC50 of 1.5 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SU0617 is a specific small molecule inhibitor of DNA repair enzyme SMUG1 with IC50 of 1.5 uM.
SU0617 demonstrates limted cross-inhibition against bacterial UDG and human NTHL1.
SU0617 is effective against different SMUG1 substrates (dU, 5-FdU, 5-OHdU, or 5-hmdU).
SU0617 is a useful tool for the study of base excision repair mechanisms involving SMUG1.

物理化学性质&存储条件

分子量 406.89
分子式 C21H15ClN4OS
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(4-((4-(4-chlorophenyl)thiazol-2-yl)amino)phenyl)nicotinamide

参考文献

1. Thacker PS, et al. ACS Med Chem Lett. 2026 May 19;17(6):1285-1293.

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