STO-609 |CAS:52029-86-4 Probechem Biochemicals

Chemical Structure : STO-609

CAS No.: 52029-86-4

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STO-609 (STO609;ST O609)

货号: PC-45723Not For Human Use, Lab Use Only.

STO-609 is a selective and cell-permeable inhibitor of CaM-KK, inhibits recombinant CaM-KKα and CaM-KKβ with Ki of 80 and 15 ng/ml.

规格	价格	库存
25 mg	￥1980	In stock
50 mg	￥3180	In stock
100 mg	￥5280	In stock
200 mg		Get quote
1 g		Get quote

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生物&药学活性

STO-609 is a selective and cell-permeable inhibitor of CaM-KK, inhibits recombinant CaM-KKα and CaM-KKβ with Ki of 80 and 15 ng/ml.
STO-609 shows no any significant effect on the downstream CaM kinases (CaM-KI and -IV, IC50 >10 ug).
STO-609 suppresses the Ca(2+)-induced activation of CaM-KIV in a dose-dependent manner in transfected HeLa cells.
STO-609 significantly reduces the endogenous activity of CaM-KK in SH-SY5Y neuroblastoma cells (1 ug/ml, 80% inhibition).

物理化学性质&存储条件

分子量	314.2943
分子式	C19H10N2O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: 5.6 mg/mL (Need ultrasonic and warming)
Chemical Name/SMILES	7H-Benzimidazo[2,1-a]benz[de]isoquinoline-3-carboxylic acid, 7-oxo-

参考文献

1. Tokumitsu H, et al. J Biol Chem. 2002 May 3;277(18):15813-8.

2. Fujiwara Y, et al. Biochemistry. 2015 Jun 30;54(25):3969-77.

3. Lin F, et al. Hepatology. 2015 Aug;62(2):505-20.

STO-609 (STO609;ST O609)

生物&药学活性

物理化学性质&存储条件

参考文献

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STO-609 (STO609;ST O609)

生物&药学活性

物理化学性质&存储条件

参考文献

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