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首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-STM3006
STM3006

Chemical Structure : STM3006

CAS No.: 2499664-52-5

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STM3006 (STM-3006)

货号: PC-24017Not For Human Use, Lab Use Only.

STM3006 is a potent, selective second-generation METTL3 inhibitor with IC50 of 5 nM, stimulates a cell-intrinsic interferon response through dsRNA formation and promotes antitumor immunity.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

STM3006 is a potent, selective second-generation METTL3 inhibitor with IC50 of 5 nM, stimulates a cell-intrinsic interferon response through dsRNA formation and promotes antitumor immunity.

物理化学性质&存储条件

分子量 519.45
分子式 C25H27BrN8
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

6-Bromo-4-(1-((6-((4,4-dimethylpiperidin-1-yl)methyl)imidazo[1,2-a]pyridin-2-yl)methyl)-1H-1,2,3-triazol-4-yl)-1H-indazole

参考文献

1. Andrew A Guirguis, et al. Cancer Discov. 2023 Oct 5;13(10):2228-2247.

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