STK16-IN-1 |CAS:1223001-53-3 Probechem Biochemicals

Chemical Structure : STK16-IN-1

CAS No.: 1223001-53-3

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STK16-IN-1 (KimH3-IN-1)

货号: PC-62875Not For Human Use, Lab Use Only.

STK16-IN-1 is a potent, highly selective ATP competitive STK16 inhibitor with IC50 of 0.295 uM, displays excellent selectivity across the kinome.

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25 mg	￥2280	In stock
100 mg	￥5580	In stock
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1 g		Get quote

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生物&药学活性

STK16-IN-1 is a potent, highly selective ATP competitive STK16 inhibitor with IC50 of 0.295 uM, displays excellent selectivity across the kinome.
STK16-IN-1 treatment results in a reduction in cell number and accumulation of binucleated cells after treatment in MCF-7 cells.
Co-treatment of STK16-IN-1 with chemotherapeutics such as cisplatin, doxorubicin, colchicine, and paclitaxel results in a slight potentiation of the antiproliferative effects of the chemotherapeutics.

物理化学性质&存储条件

分子量	293.301
分子式	C17H12FN3O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-Fluoro-3-methylphenyl)-1,7-dihydro-2H-pyrrolo[2,3-h]-1,6-naphthyridin-2-one

参考文献

1. Liu F, et al. ACS Chem Biol. 2016 Jun 17;11(6):1537-43.

STK16-IN-1 (KimH3-IN-1)

生物&药学活性

物理化学性质&存储条件

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STK16-IN-1 (KimH3-IN-1)

生物&药学活性

物理化学性质&存储条件

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