STIRUR 41 | USP7 inhibitor | Probechem Biochemicals

Chemical Structure : STIRUR 41

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STIRUR 41 (STIRUR-41, STIR UR 41)

货号: PC-24793Not For Human Use, Lab Use Only.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

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生物&药学活性

STIRUR 41 (STIRUR-41, STIR UR 41) is a small molecule USP-7 inhibitor with IC50 of 2.77 uM in HTLA-230 cells, STIRUR 41 (5-10 uM) STIRUR 41 induces a remarkable decrease in USP-7 protein levels in HTLA-230 cells.
STIRUR 41 exerts a strong inhibitory effect on interleukin 8 or N-formyl-methionyl-leucyl-phenylalanine-induced chemotaxis of human neutrophils.
STIRUR 41 is able to counteract the HTLA-230 cells ability to form capillary-like structures, does not affect the viability and tumorigenicity of ACN and HTLA-230 cells, does not induce changes in p38MAPK and phosphop38MAPK levels of ACN and HTLA-230 cells.

物理化学性质&存储条件

分子量	350.35
分子式	C16H19FN4O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	ethyl 5-(3-(3-fluorophenyl)ureido)-1-(2-hydroxypropyl)-1H-pyrazole-4-carboxylate

参考文献

1. Marengo B, et al. Oncotarget. 2020 Sep 15;11(37):3459-3472.

2. Elva Morretta, et al. Int J Mol Sci. 2023 May 24;24(11):9200.

STIRUR 41 (STIRUR-41, STIR UR 41)

生物&药学活性

物理化学性质&存储条件

参考文献

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STIRUR 41 (STIRUR-41, STIR UR 41)

生物&药学活性

物理化学性质&存储条件

参考文献

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