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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Glucose Transporter (GLUT)-STF-31
STF-31

Chemical Structure : STF-31

CAS No.: 724741-75-7

STF-31 (STF31)

货号: PC-45543Not For Human Use, Lab Use Only.

A selective GLUT1 inhibitor that does not bind to other glucose transporters.

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10 mg ¥880 In stock
25 mg ¥1480 In stock
50 mg ¥2380 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

STF-31 is a selective GLUT1 inhibitor with IC50 of 1 uM, does not bind to other glucose transporters.
STF-31 selectively kills RCCs by specifically targeting glucose uptake through GLUT1 and exploiting the unique dependence of these cells on GLUT1 for survival.
STF-31 also inhibits the enzymatic activity of NAMPT in a biochemical assay in vitro.

物理化学性质&存储条件

分子量 423.5279
分子式 C23H25N3O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 34 mg/mL

Chemical Name/SMILES

Benzamide, 4-[[[[4-(1,1-dimethylethyl)phenyl]sulfonyl]amino]methyl]-N-3-pyridinyl-

参考文献

1. Chan DA, et al. Sci Transl Med. 2011 Aug 3;3(94):94ra70.

2. Adams DJ, et al. ACS Chem Biol. 2014 Oct 17;9(10):2247-54.

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