Chemical Structure : STF-31
CAS No.: 724741-75-7
货号: PC-45543Not For Human Use, Lab Use Only.
A selective GLUT1 inhibitor that does not bind to other glucose transporters.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | ¥880 | In stock | |
25 mg | ¥1480 | In stock | |
50 mg | ¥2380 | In stock | |
100 mg | Get quote |
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STF-31 is a selective GLUT1 inhibitor with IC50 of 1 uM, does not bind to other glucose transporters.
STF-31 selectively kills RCCs by specifically targeting glucose uptake through GLUT1 and exploiting the unique dependence of these cells on GLUT1 for survival.
STF-31 also inhibits the enzymatic activity of NAMPT in a biochemical assay in vitro.
分子量 | 423.5279 | |
分子式 | C23H25N3O3S | |
外观性状 | Solid | |
储存条件 |
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Solubility |
DMSO: ≥ 34 mg/mL |
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Chemical Name/SMILES |
Benzamide, 4-[[[[4-(1,1-dimethylethyl)phenyl]sulfonyl]amino]methyl]-N-3-pyridinyl- |
1. Chan DA, et al. Sci Transl Med. 2011 Aug 3;3(94):94ra70.
2. Adams DJ, et al. ACS Chem Biol. 2014 Oct 17;9(10):2247-54.
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