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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-IRE1-STF-083010
STF-083010

Chemical Structure : STF-083010

CAS No.: 307543-71-1

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STF-083010 (STF083010)

货号: PC-44755Not For Human Use, Lab Use Only.

STF-083010 is a potent and selective IRE1 endoribonuclease inhibitor without affecting IRE1 kinase activity.

规格 价格 库存 数量
10 mg ￥780 In stock
25 mg ￥1280 In stock
50 mg ￥1980 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

STF-083010 is a potent and selective IRE1 endoribonuclease inhibitor without affecting IRE1 kinase activity.
STF-083010  shows significant antimyeloma activity in model human MM xenografts.

物理化学性质&存储条件

分子量 317.3828
分子式 C15H11NO3S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-Thiophenesulfonamide, N-[(2-hydroxy-1-naphthalenyl)methylene]-

参考文献

1. Papandreou I, et al. Blood. 2011 Jan 27;117(4):1311-4.

2. Chien W, et al. Oncotarget. 2014 Jul 15;5(13):4881-94.

3. Sun H, et al. Oncotarget. 2016 Apr 5;7(14):18736-49.

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