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首页-小分子抑制剂&激动剂-JAK/STAT Signaling-STAT-STAT5b inhibitor 7
STAT5b inhibitor 7

Chemical Structure : STAT5b inhibitor 7

CAS No.: 1818390-58-7

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STAT5b inhibitor 7 (Capstafin prodrug)

货号: PC-61628Not For Human Use, Lab Use Only.

STAT5b inhibitor 7 (Capstafin prodrug) is the pivaloyloxymethyl ester prodrug of Capstafin, which is a potent, selective STAT5b inhibitor with Ki of 0.34 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    STAT5b inhibitor 7 (Capstafin prodrug) is the pivaloyloxymethyl ester prodrug of Capstafin, which is a potent, selective STAT5b inhibitor with Ki of 0.34 uM.
    STAT5b inhibitor 7 inhibits STAT5b with selectivity over STAT5a in human tumor cells, inhibits cell viability and induces apoptosis in human tumor cells in a STAT5-dependent manner.

    物理化学性质&存储条件

    分子量 909.941
    分子式 C41H69NO17P2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    ((((4-((8-methylnonanamido)methyl)-1,2-phenylene)bis(oxy))bis(oxo-l5-phosphanetriyl))tetrakis(oxy))tetrakis(methylene) tetrakis(2,2-dimethylpropanoate)

    参考文献

    1. Elumalai N, et al. ACS Chem Biol. 2015 Dec 18;10(12):2884-90.

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