STAT5-IN-1 |CAS:285986-31-4 Probechem Biochemicals

Chemical Structure : STAT5-IN-1

CAS No.: 285986-31-4

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STAT5-IN-1

货号: PC-61311Not For Human Use, Lab Use Only.

STAT5-IN-1 is a selective, small molecule inhibitor of the transcription factor STAT5 with IC50 of 47±17 uM in FP assays.

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25 mg	￥1380	In stock
50 mg	￥2280	In stock
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生物&药学活性

STAT5-IN-1 is a selective, small molecule inhibitor of the transcription factor STAT5 with IC50 of 47±17 uM in FP assays.
STAT5-IN-1 shows little to no inhibition for STAT1, STAT3 and Lck (<40% inhibition at 500 uM).
STAT5-IN-1 selectively inhibits the function of the STAT5b domain and STAT5 DNA binding in vitro, and selectively inhibits activation of STAT5 in K562 cells.

物理化学性质&存储条件

分子量	293.28
分子式	C16H11N3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-Pyridinecarboxylic acid, [(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazide (9CI)

参考文献

1. Müller J, et al. Chembiochem. 2008 Mar 25; 9(5):723-7.

STAT5-IN-1

生物&药学活性

物理化学性质&存储条件

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STAT5-IN-1

生物&药学活性

物理化学性质&存储条件

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