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首页-小分子抑制剂&激动剂-GPCR-Adenosine Receptor-ST1535
ST1535

Chemical Structure : ST1535

CAS No.: 496955-42-1

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ST1535 (ST 1535;ST-1535)

货号: PC-70072Not For Human Use, Lab Use Only.

ST1535 is a potent, selective A2A adenosine receptor antagonist with Ki of 6.6 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ST1535 is a potent, selective A2A adenosine receptor antagonist with Ki of 6.6 nM.
ST1535 displays 10, 58 and >160-fold selectivity over A1, A2B and A3 receptors, respectively.
ST1535 increases locomotor activity in animal models of Parkinson׳s disease.

物理化学性质&存储条件

分子量 272.316
分子式 C12H16N8
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-butyl-9-methyl-8-(2H-1,2,3-triazol-2-yl)-9H-purin-6-amine

参考文献

1. Minetti P, et al. J Med Chem. 2005 Nov 3;48(22):6887-96.

2. Rose S, et al. Eur J Pharmacol. 2006 Sep 28;546(1-3):82-7.

3. Rose S, et al. Brain Res. 2007 Feb 16;1133(1):110-4.

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