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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Adenylate Cyclase-ST034307
ST034307

Chemical Structure : ST034307

CAS No.: 133406-29-8

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ST034307 (ST 034307, ST-034307)

货号: PC-70041Not For Human Use, Lab Use Only.

ST034307 (ST 034307, ST-034307) is a potent, selective adenylyl cyclase 1 (AC1) with IC50 of 2.3 uM.

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10 mg ￥980 In stock
25 mg ￥1780 In stock
100 mg ￥4580 In stock
500 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ST034307 (ST 034307, ST-034307) is a potent, selective adenylyl cyclase 1 (AC1) with IC50 of 2.3 uM.
ST034307 shows no activity against other AC isoforms.
ST034307 inhibits Ca2+-stimulated cAMP accumulation in HEK cells, also inhibits AC1 activity stimulated by forskolin- and Gαs-coupled receptors in HEK-AC1 cells.
ST034307 reduces pain responses in a mouse model of inflammatory pain.

物理化学性质&存储条件

分子量 297.95
分子式 C10H4Cl4O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

6-chloro-2-(trichloromethyl)-4H-chromen-4-one

参考文献

1. Brust TF, et al. Sci Signal. 2017 Feb 21;10(467). pii: eaah5381.

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