ST-193 | LASV inhibitor | Probechem Biochemicals

Chemical Structure : ST-193

CAS No.: 489416-12-8

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ST-193 (ST193, ST 193)

货号: PC-42388Not For Human Use, Lab Use Only.

ST-193 (ST193) is a potent, selective, broad-spectrum arenavirus entry inhibitor with IC50 of 1.6 nM against LASV pseudotypes, targets arenavirus envelope glycoprotein.

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10 mg	￥2980	In stock
25 mg	￥4980	In stock
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生物&药学活性

ST-193 (ST193) is a potent, selective, broad-spectrum arenavirus entry inhibitor with IC50 of 1.6 nM against LASV pseudotypes, targets arenavirus envelope glycoprotein.
ST-193 also inhibits pseudotypes generated with other arenavirus envelopes with IC50 of 0.2-12 nM, but exhibited no antiviral activity against pseudotypes incorporating either the GP from the LASV-related arenavirus LCMV or the unrelated G protein from vesicular stomatitis virus (IC50>10 uM).
ST-193 exhibits antiviral activity against Lassa virus (LASV) in a guinea pig model (i.p.).

物理化学性质&存储条件

分子量	371.4748
分子式	C24H25N3O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 150 mg/mL
Chemical Name/SMILES	1H-Benzimidazol-5-amine, 1-(4-methoxyphenyl)-N-[[4-(1-methylethyl)phenyl]methyl]-

参考文献

1. Larson RA, et al. J Virol. 2008 Nov;82(21):10768-75.

2. York J, et al. J Virol. 2008 Nov;82(21):10932-9.

3. Cashman KA, et al. Antiviral Res. 2011 Apr;90(1):70-9.

4. Dai D, et al. Bioorg Med Chem Lett. 2013 Feb 1;23(3):744-9.

ST-193 (ST193, ST 193)

生物&药学活性

物理化学性质&存储条件

参考文献

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ST-193 (ST193, ST 193)

生物&药学活性

物理化学性质&存储条件

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