SRT 2183 |CAS:1001908-89-9 Probechem Biochemicals

Chemical Structure : SRT 2183

CAS No.: 1001908-89-9

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SRT 2183 (SRT2183)

货号: PC-63005Not For Human Use, Lab Use Only.

SRT 2183 is a potent, selective SIRT1 activator with EC1.5 of 0.36 uM, displays good selectivity for activation of SIRT1 versus SIRT2 and SIRT3 (EC1.5>300 uM) and is more potent than Resveratrol.

规格	价格	库存
5 mg	￥980	In stock
10 mg	￥1480	In stock
25 mg	￥2580	In stock
50 mg	￥3980	In stock
100 mg		Get quote

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生物&药学活性

SRT 2183 is a potent, selective SIRT1 activator with EC1.5 of 0.36 uM, displays good selectivity for activation of SIRT1 versus SIRT2 and SIRT3 (EC1.5>300 uM) and is more potent than Resveratrol.
SRT 2183 improves insulin sensitivity, lower plasma glucose, and increase mitochondrial capacity in obese mice model.

物理化学性质&存储条件

分子量	468.575
分子式	C27H24N4O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[2-[3-[[(3R)-3-hydroxypyrrolidin-1-yl]methyl]imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]naphthalene-2-carboxamide

参考文献

1. Milne JC, et al. Nature. 2007 Nov 29;450(7170):712-6.

2. Pacholec M, et al. J Biol Chem. 2010 Mar 12;285(11):8340-51.

3. Gurt I, et al. PLoS One. 2015 Jul 30;10(7):e0134391.

SRT 2183 (SRT2183)

生物&药学活性

物理化学性质&存储条件

参考文献

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SRT 2183 (SRT2183)

生物&药学活性

物理化学性质&存储条件

参考文献

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