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首页-小分子抑制剂&激动剂-Epigenetics-Sirtuin -SRT2104
SRT2104

Chemical Structure : SRT2104

CAS No.: 1093403-33-8

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SRT2104 (GSK2245840)

货号: PC-47061Not For Human Use, Lab Use Only.

SRT2104 (GSK2245840) is a highly selective small molecule activator of the NAD+ dependent deacetylase SIRT1.

规格 价格 库存 数量
5 mg ￥880 In stock
10 mg ￥1280 In stock
25 mg ￥2180 In stock
50 mg ￥3580 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SRT2104 (GSK2245840) is a highly selective small molecule activator of the NAD+ dependent deacetylase SIRT1, increases Sirt1 protein with no effect on Sirt1 mRNA level.

物理化学性质&存储条件

分子量 516.638
分子式 C26H24N6O2S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-methyl-N-[2-[3-(4-morpholinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-2-(3-pyridinyl)-5-thiazolecarboxamide

参考文献

1. Ethan Hoffmann, et al. Br J Clin Pharmacol. 2013 Jan;75(1):186-96.

2. Mercken EM, et al. Aging Cell. 2014 Oct;13(5):787-96.

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