SRT 1720 |CAS:925434-55-5 Probechem Biochemicals

Chemical Structure : SRT 1720

CAS No.: 925434-55-5

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SRT 1720 (SRT-1720;SRT1720)

货号: PC-42642Not For Human Use, Lab Use Only.

SRT 1720 is a potent, selective SIRT1 activator with EC1.5 of 0.16 uM.

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10 mg	￥1280	In stock
25 mg	￥1980	In stock
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生物&药学活性

SRT 1720 is a potent, selective SIRT1 activator with EC1.5 of 0.16 uM.
SRT 1720 displays good selectivity for activation of SIRT1 versus SIRT2 (EC1.5=37 uM) and SIRT3 (EC1.5>300 uM).
SRT 1720 is 1,000-fold more potent than resveratrol.
SRT 1720 improves insulin sensitivity, lower plasma glucose, and increases mitochondrial capacity in obese mice model.

物理化学性质&存储条件

分子量	469.5614
分子式	C25H23N7OS
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Quinoxalinecarboxamide, N-[2-[3-(1-piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]-

参考文献

1. Milne JC, et al. Nature. 2007 Nov 29;450(7170):712-6.

2. Pacholec M, et al. J Biol Chem. 2010 Mar 12;285(11):8340-51.

3. Funk JA, et al. J Pharmacol Exp Ther. 2010 May;333(2):593-601.

SRT 1720 (SRT-1720;SRT1720)

生物&药学活性

物理化学性质&存储条件

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SRT 1720 (SRT-1720;SRT1720)

生物&药学活性

物理化学性质&存储条件

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