SRT1460 |CAS:925432-73-1 Probechem Biochemicals

Chemical Structure : SRT1460

CAS No.: 925432-73-1

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SRT1460 (SRT1460, SRT-1460)

货号: PC-63004Not For Human Use, Lab Use Only.

SRT1460 is a potent, selective SIRT1 activator with EC1.5 of 2.9 uM, displays good selectivity for activation of SIRT1 versus SIRT2 and SIRT3 (EC1.5>300 uM) and is more potent than Resveratrol.

规格	价格	库存
5 mg	￥880	In stock
10 mg	￥1280	In stock
25 mg	￥1980	In stock
50 mg	￥3280	In stock
100 mg		Get quote

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生物&药学活性

SRT1460 is a potent, selective SIRT1 activator with EC1.5 of 2.9 uM, displays good selectivity for activation of SIRT1 versus SIRT2 and SIRT3 (EC1.5>300 uM) and is more potent than Resveratrol.
SRT1460 improves insulin sensitivity, lowers plasma glucose, and increases mitochondrial capacity in obese mice model.

物理化学性质&存储条件

分子量	507.609
分子式	C26H29N5O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3,4,5-Trimethoxy-N-[2-[3-(1-piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl]phenyl]benzamide

参考文献

1. Milne JC, et al. Nature. 2007 Nov 29;450(7170):712-6.

2. Pacholec M, et al. J Biol Chem. 2010 Mar 12;285(11):8340-51.

3. Hubbard BP, et al. Science. 2013 Mar 8;339(6124):1216-9.

4. Chini CC, et al. Clin Cancer Res. 2016 May 15;22(10):2496-507.

SRT1460 (SRT1460, SRT-1460)

生物&药学活性

物理化学性质&存储条件

参考文献

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SRT1460 (SRT1460, SRT-1460)

生物&药学活性

物理化学性质&存储条件

参考文献

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