SRP-001 | Analgesic agent | Probechem Biochemicals

Chemical Structure : SRP-001

加入收藏

SRP-001 (SRP001)

货号: PC-20837Not For Human Use, Lab Use Only.

SRP-001 is a non-opioid and non-hepatotoxic small molecule ApAP analog, induces analgesia via N-arachidonoylphenolamine (AM404) formation, and generates higher amounts of AM404 than ApAP.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

SRP-001 is a non-opioid and non-hepatotoxic small molecule ApAP analog, induces analgesia via N-arachidonoylphenolamine (AM404) formation, and generates higher amounts of AM404 than ApAP.
SRP-001 is devoid of hepatotoxicity due to lack of NAPQI formation and protection of hepatic tight junctions integrity.
SRP-001 has comparable analgesia in pain models, including the complete Freund's adjuvant (CFA) inflammatory von Frey.
SRP-001 shows modulation of pain-related gene expression and cell signaling pathways, including the endocannabinoid, mechanical nociception, and fatty acid amide hydrolase (FAAH) pathways.
SRP-001 regulates the expression of key genes encoding FAAH, 2-AG, CNR1, CNR2, TRPV4, and voltage-gated Ca2+ channel.

物理化学性质&存储条件

分子量	405.47
分子式	C19H23N3O5S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N,N-diethyl-2-(N-(2-((4-hydroxyphenyl)amino)-2-oxoethyl)sulfamoyl)benzamide

参考文献

1. Hernan Bazan, et al. Res Sq. 2023 May 4;rs.3.rs-2883310.

SRP-001 (SRP001)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

SRP-001 (SRP001)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.