SRI-35241 | TGF-β inhibitor | Probechem Biochemicals

Chemical Structure : SRI-35241

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SRI-35241 (SRI 35241 )

货号: PC-21885Not For Human Use, Lab Use Only.

SRI-35241 is a potent inhibitor of thrombospondin 1 activation of TGF-β, specifically inhibits TGF-β activation mediated through TSP-1 with pIC50 of 8.12 nM, 79% inhibition at 100 nM.

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生物&药学活性

SRI-35241 is a potent inhibitor of thrombospondin 1 activation of TGF-β, specifically inhibits TGF-β activation mediated through TSP-1 with pIC50 of 8.12 nM, 79% inhibition at 100 nM.

物理化学性质&存储条件

分子量	258.32
分子式	C11H22N4O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-acetamido-5-amino-N-(1-amino-2-methyl-1-oxopropan-2-yl)pentanamide

参考文献

1. Mark J Suto, et al. ACS Med Chem Lett. 2020 May 7;11(6):1130-1136.

SRI-35241 (SRI 35241 )

生物&药学活性

物理化学性质&存储条件

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SRI-35241 (SRI 35241 )

生物&药学活性

物理化学性质&存储条件

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