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首页-小分子抑制剂&激动剂-TGF-beta/Smad-TGF beta Receptor (TGFBR)-SRI-31277
SRI-31277

Chemical Structure : SRI-31277

CAS No.: 1637468-93-9

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SRI-31277 (SRI 31277)

货号: PC-21884Not For Human Use, Lab Use Only.

SRI-31277 is a tripeptide inhibitor of thrombospondin 1 activation of TGF-β, specifically inhibits TGF-β activation mediated through TSP-1 with pIC50 of 8.28 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SRI-31277 is a tripeptide inhibitor of thrombospondin 1 activation of TGF-β, specifically inhibits TGF-β activation mediated through TSP-1 with pIC50 of 8.28 nM.

物理化学性质&存储条件

分子量 387.48
分子式 C17H33N5O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-2-((S)-2-acetamido-3-hydroxypropanamido)-6-amino-N-((S)-1-amino-4-methyl-1-oxopentan-2-yl)hexanamide

参考文献

1. Lu A, et al. Am. J. Pathol. 2016, 186, 678–690.

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