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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Cdc2-like Kinase (CLK)-SRI-29329
SRI-29329

Chemical Structure : SRI-29329

CAS No.: 2086809-58-5

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SRI-29329 (SRI29329;SRI 29329)

货号: PC-61027Not For Human Use, Lab Use Only.

SRI-29329 (SRI29329) is a potent, specific CDC-like kinase (CLK) inhibitor with IC50 of 78, 16 and 86 nM for CLK1, 2 and 4, respectively.

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5 mg ￥2280 In stock
10 mg ￥3680 In stock
25 mg ￥5680 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SRI-29329 (SRI29329) is a potent, specific CDC-like kinase (CLK) inhibitor with IC50 of 78, 16 and 86 nM for CLK1, 2 and 4, respectively.
SRI-29329 shows no significant activity for CLK3, CDK1, CDK4 and CDK6 (IC50>1,000 nM).

物理化学性质&存储条件

分子量 399.927
分子式 C20H26ClN7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N2-((1S,2S)-2-aminocyclohexyl)-N6-(3-chlorophenyl)-9-isopropyl-9H-purine-2,6-diamine

参考文献

1. Shi Y, et al. Bioorg Med Chem Lett. 2017 Feb 1;27(3):406-412.

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