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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Chloride Channel-SRA-36
SRA-36

Chemical Structure : SRA-36

CAS No.:

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SRA-36 (SRA36)

货号: PC-28701Not For Human Use, Lab Use Only.

SRA-36 is a potent and selective inhibitor of kidney CLC-K chloride channel ClC-Ka with IC50 of 6.6 uM and Ki of 3.8 uM, inhibits chloride currents sustained by A447T CLC-Ka and Y315F CLC-Ka.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SRA-36 is a potent and selective inhibitor of kidney CLC-K chloride channel ClC-Ka with IC50 of 6.6 uM and Ki of 3.8 uM, inhibits chloride currents sustained by A447T CLC-Ka and Y315F CLC-Ka.

物理化学性质&存储条件

分子量 328.37
分子式 C22H16O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-benzyl-3-phenylbenzofuran-2-carboxylic acid

参考文献

1. Liantonio A, et al. J Hypertens. 2016;34(5):981-992.

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