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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-PPAR-SR16832
SR16832

Chemical Structure : SR16832

CAS No.: 2088135-12-8

SR16832 (SR-16832, SR 16832)

货号: PC-62344Not For Human Use, Lab Use Only.

SR16832 is a dual-site, covalent and allosteric antagonist of PPARγ, inhibits cellular allosteric activation of PPARγ by rosiglitazone.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SR16832 is a dual-site, covalent and allosteric antagonist of PPARγ, inhibits cellular allosteric activation of PPARγ by rosiglitazone.
SR16832 is a useful, complementary chemical tools for researchers to use to simultaneously inhibit both orthosteric and allosteric ligand-induced cellular activation of PPARγ.

物理化学性质&存储条件

分子量 357.75
分子式 C17H12ClN3O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-chloro-N-(6-methoxyquinolin-4-yl)-5-nitrobenzamide

参考文献

1. Brust R, et al. ACS Chem Biol. 2017 Apr 21;12(4):969-978.

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