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首页-小分子抑制剂&激动剂-GPCR-Opioid Receptor-SR16435
SR16435

Chemical Structure : SR16435

CAS No.: 857262-16-9

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SR16435 (SR-16435)

货号: PC-61536Not For Human Use, Lab Use Only.

SR16435 is a mixed NOP/μ-opioid partial agonist with equally high affinity (Ki=29 nM) for both NOP and μ-opioid receptors.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    SR16435 is a mixed NOP/μ-opioid partial agonist with equally high affinity (Ki=29 nM) for both NOP and μ-opioid receptors.
    SR16435 possesses analgesic activity with reduced tolerance development and diminished reward in mice.

    物理化学性质&存储条件

    分子量 338.495
    分子式 C22H30N2O
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    1-(1-(bicyclo[3.3.1]nonan-9-yl)piperidin-4-yl)indolin-2-one

    参考文献

    1. Khroyan TV, et al. J Pharmacol Exp Ther. 2007 Feb;320(2):934-43.

    2. Zaveri NT, et al. J Med Chem. 2004 Jun 3;47(12):2973-6.

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