SR10221 | PPARγ inverse agonist | Probechem Biochemicals

Chemical Structure : SR10221

CAS No.: 1415321-64-0

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SR10221 (SR 10221)

货号: PC-49401Not For Human Use, Lab Use Only.

SR10221 is a potent, selective PPARγ inverse agonist with IC50 of 13 nM in biochemical peptide recruitment assays, represses downstream PPARγ target genes leading to growth inhibition in bladder cancer cell lines.

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10 mg	￥1280	In stock
25 mg	￥2180	In stock
50 mg	￥3580	In stock
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SR10221 is a potent, selective PPARγ inverse agonist with IC50 of 13 nM in biochemical peptide recruitment assays, represses downstream PPARγ target genes leading to growth inhibition in bladder cancer cell lines.

物理化学性质&存储条件

分子量	561.119
分子式	C33H37ClN2O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-(5-((5-(((S)-1-(4-(tert-butyl)phenyl)ethyl)carbamoyl)-2,3-dimethyl-1H-indol-1-yl)methyl)-2-chlorophenoxy)propanoic acid

参考文献

1. Sean Irwin, et al. J Biol Chem. 2022 Sep 28;298(11):102539.

SR10221 (SR 10221)

生物&药学活性

物理化学性质&存储条件

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SR10221 (SR 10221)

生物&药学活性

物理化学性质&存储条件

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