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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-GABA Transporter (GAT)-SR-THAP
SR-THAP

Chemical Structure : SR-THAP

CAS No.: 3098361-74-8

SR-THAP

货号: PC-25993Not For Human Use, Lab Use Only.

SR-THAP is a selective inhibitor of human GABA transporter GAT3 with IC50 of 4.9 uM, shows no inhibition on GAT1.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SR-THAP is a selective inhibitor of human GABA transporter GAT3 with IC50 of 4.9 uM, shows no inhibition on GAT1.

物理化学性质&存储条件

分子量 517.62
分子式 C31H35NO6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-Pyrrolidineacetic acid, α-hydroxy-1-[(2E)-4,4,4-tris(4-methoxyphenyl)-2-buten-1-yl]-, (αS,2R)-

参考文献

1. Mortensen JS, et al. Nat Commun. 2026 Jan 29. doi: 10.1038/s41467-026-68479-0.

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