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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-SPI009
SPI009

Chemical Structure : SPI009

CAS No.: 1008671-41-7

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SPI009 (SPI 009)

货号: PC-61788Not For Human Use, Lab Use Only.

SPI009 is a novel antipersister compound active against P. aeruginosa.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    SPI009 is a novel antipersister compound active against P. aeruginosa, reduces the number of persisters up to 100,000-fold in both lab strains and clinical isolates of P. aeruginosa when combined with distinct classes of antibiotics.
    SPI009 efficiently kills persister cells with minor cytotoxicity, and causes no erythrocyte damage.

    物理化学性质&存储条件

    分子量 340.244
    分子式 C17H19Cl2NO2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    1-[(2,4-dichlorophenethyl)amino]-3-phenoxypropan-2-ol

    参考文献

    1. Liebens V, et al. Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00836-17.

    2. Defraine V, et al. Front Microbiol. 2017 Dec 22;8:2585.

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