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首页-抗体药物偶连体和PROTACs-ADCs Linker/Click Chemistry-SPDP
SPDP

Chemical Structure : SPDP

CAS No.: 68181-17-9

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SPDP

货号: PC-42088Not For Human Use, Lab Use Only.

A heterobifunctional crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls.

规格 价格 库存 数量
50 mg ￥960 In stock
100 mg ￥1680 In stock
200 mg ￥2880 In stock
500 mg ￥5840 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A heterobifunctional crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls.

物理化学性质&存储条件

分子量 312.3647
分子式 C12H12N2O4S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Propanoic acid, 3-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester

参考文献

1. Woo BH, et al. Arch Pharm Res. 1994 Dec;17(6):452-7.

2. Lobedanz S, et al. Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4612-7.

3. Ma G, et al. Int J Nanomedicine. 2013;8:1029-35.

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