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首页-抗体药物偶连体和PROTACs-ADCs Linker/Click Chemistry-SPDB
SPDB

Chemical Structure : SPDB

CAS No.: 115088-06-7

SPDB

货号: PC-43038Not For Human Use, Lab Use Only.

SPDB is a disulfide chemical linker for antibody-drug conjugates (ADCs)..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

SPDB is a disulfide chemical linker for antibody-drug conjugates (ADCs).

物理化学性质&存储条件

分子量 326.3913
分子式 C13H14N2O4S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Butanoic acid, 4-(2-pyridinyldithio)-, 2,5-dioxo-1-pyrrolidinyl ester

参考文献

1. Cumber AJ, et al. Bioconjug Chem. 1992 Sep-Oct;3(5):397-401.

2. Erickson HK, et al. Cancer Res. 2006 Apr 15;66(8):4426-33.

3. Ikeda H, et al. Clin Cancer Res. 2009 Jun 15;15(12):4028-37.

4. Zhao RY, et al. J Med Chem. 2011 May 26;54(10):3606-23.

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