SPAA-52 | LMW-PTP inhibitor | Probechem Biochemicals

Chemical Structure : SPAA-52

CAS No.: 2837000-75-4

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SPAA-52 (LMW-PTP inhibitor SPAA52)

货号: PC-49364Not For Human Use, Lab Use Only.

SPAA-52 is a highly potent, selective inhibitor of the low-molecular-weight protein tyrosine phosphatase (LMW-PTP) with Ki of 1.2 nM, >8000-fold selectivity over other PTPs.

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5 mg	￥1880	In stock
25 mg	￥4580	In stock
50 mg	￥7580	In stock
100 mg		Get quote

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生物&药学活性

SPAA-52 is a highly potent, selective inhibitor of the low-molecular-weight protein tyrosine phosphatase (LMW-PTP) with Ki of 1.2 nM, >8000-fold selectivity over other PTPs.
SPAA-52 shows equipotent potency across rat, mouse and human LMW-PTP enzymes with IC50 of 3, 3 and 4 nM, respectively.

物理化学性质&存储条件

分子量	388.030
分子式	C8H8Br2N2O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	((3,5-dibromo-4-methylphenyl)carbamoyl)sulfamic acid

参考文献

1. Rongjun He, et al. J Med Chem. 2022 Oct 27;65(20):13892-13909.

SPAA-52 (LMW-PTP inhibitor SPAA52)

生物&药学活性

物理化学性质&存储条件

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SPAA-52 (LMW-PTP inhibitor SPAA52)

生物&药学活性

物理化学性质&存储条件

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