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首页-小分子抑制剂&激动剂-Ras-Raf-MAPK-ERK Pathway-Ras-SOS2 binder 1
SOS2 binder 1

Chemical Structure : SOS2 binder 1

CAS No.: 690696-36-7

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SOS2 binder 1

货号: PC-23829Not For Human Use, Lab Use Only.

SOS2 binder 1 is a selective quinazoline-based compound that binds to the catalytic site of SOS2 with SPR KD of 4.6 uM, shows no binding to SOS1 up 200 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

SOS2 binder 1 is a selective quinazoline-based compound that binds to the catalytic site of SOS2 with SPR KD of 4.6 uM, shows no binding to SOS1 up 200 uM.

物理化学性质&存储条件

分子量 335.41
分子式 C19H21N5O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-((4-(4-Methylpiperazin-1-yl)quinazolin-2-yl)amino)phenol

参考文献

1. Zak KM, et al. J Med Chem. 2025 Jan 17. doi: 10.1021/acs.jmedchem.4c02007.

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